My uncle is a prosperous businessman, my aunt, unfortunately, is quite …

Analyze the question: The underlined word is "prosperous" (the underline isn't visible here, but the sentence makes clear it refers to "prosperous"). We need the word that is nearest in meaning to the opposite of "prosperous" and that also fits the gap in the sentence.

Concept: "Prosperous" means successful, flourishing, especially financially. Its antonym is something like "unsuccessful" or "poor/failing."

Step-by-step:

1. Sentence structure: "My uncle is a prosperous businessman, my aunt, unfortunately, is quite __." The word "unfortunately" signals a contrast with the uncle's success.
2. Check each option: • A. unskillful: this means lacking skill, which is not the same as lacking success or wealth. • B. domestic: it relates to the home and has no connection to prosperity. • C. unsuccessful: this is the direct opposite of prosperous (successful) and fits the contrast. • D. unqualified: this means lacking qualifications, which is not the opposite of prosperity.
3. Only C gives both the opposite meaning and a sentence that makes sense.

Answer: C. unsuccessful.

Tip: In opposite-meaning questions, first state the meaning of the key word in simple terms (prosperous = successful/wealthy). Then look for the option that reverses that exact idea. Also watch for clue words like "unfortunately," "but," and "however," which signal contrast.