JAMB 2021 Biology · Question 33
If a DNA strand has a base sequence TCA, its complementary strand must be?
Options
- A.ATG
- B.TAG
- C.GAT
- D.AGT
Answer: D. AGT
Explanation written with AI and checked against the answer key
Analyze the question: You're given one DNA strand, TCA, and asked for its complementary strand.
Concept: base pairing in DNA
- Adenine (A) pairs with Thymine (T)
- Guanine (G) pairs with Cytosine (C)
(In RNA, thymine is replaced by uracil (U), but this question is about DNA, so we use T.)
Step-by-step solution:
Original strand: T C A
- T pairs with A
- C pairs with G
- A pairs with T
Complementary strand: A G T
Check against the options:
- A. ATG: wrong, because C should pair with G in the second position, not T
- B. TAG: wrong, because it doesn't pair correctly at any position
- C. GAT: wrong, because T should pair with A in the first position, not G
- D. AGT: correct
Exam tip: Remember "Apples in the Tree, Cars in the Garage": A-T and C-G. Replace each base with its partner, one at a time. Also note that the complementary strand is written antiparallel in real molecules (so it would read 3'→5' alongside the original). JAMB usually just wants the direct base-by-base pairing, as here.
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