The following are functions of the liver EXCEPT

Analyze the question: We need the one option that is NOT a function of the liver.

Concept: Functions of the liver

• Deamination of excess amino acids, producing urea (A is a function).
• Excretion of bile pigments (bilirubin) from the breakdown of haemoglobin, which are released in bile (B is a function).
• Production of heat, since the liver is metabolically very active (D is a function).
• Storage of vitamins (A, D, B12) and minerals such as iron (E is a function).
• Storage of glycogen, regulation of blood sugar, detoxification of drugs and alcohol, and production of bile, fibrinogen, prothrombin and plasma proteins such as albumin.

Step by step:

• A: True. Excess amino acids are deaminated in the liver.
• B: True. Bile pigments are excreted via bile.
• C: "Manufacture of blood plasma." The liver makes some plasma proteins (albumin, fibrinogen, prothrombin), but it does not manufacture blood plasma as a whole. Plasma is mostly water, with salts, glucose, hormones and other substances absorbed from the gut and made by other organs. The statement is therefore not accurate, and it is the intended "exception."
• D: True. The liver is a major source of body heat.
• E: True. The liver stores vitamins and minerals.

Note on the wording: Option C is partly defensible, because the liver makes plasma proteins. However, "blood plasma" as a whole is not made by the liver.

Exam tip: In "EXCEPT" questions, test each option against what you know. Watch for options that sound close to a real function but overstate it. The liver makes plasma proteins, not the whole plasma. Remember: the liver makes plasma proteins, bile, and urea.